MRSA ICD-10 codes
There is no single ICD-10 code for MRSA. Which code you assign depends on whether MRSA is causing a documented condition, is an infection with no stated site, or is colonisation found on a screening swab — and the sequencing rules matter as much as the codes.
Written by David Roberts, editor · Updated
Checked against current CDC and IDSA guidance. Not medically reviewed. How we source this
The short answer
In ICD-10-CM, B95.62 identifies MRSA as the cause of a condition coded elsewhere and is always a secondary code. A49.02 is for a MRSA infection with no documented site or condition. Z22.322 is for carrier status — colonisation, not infection. Pneumonia and sepsis have their own combination codes (J15.212 and A41.02) that already include the organism.
This page is written for coders, clinical documentation specialists and billing staff. If you are looking for the condition itself, start with MRSA symptoms or MRSA treatment.
MRSA code reference table
| Code | Description | When to use it |
|---|---|---|
| B95.62 | Methicillin resistant Staphylococcus aureus infection as the cause of diseases classified elsewhere | The workhorse code. Assign it as an additional code after the code for the infection itself — cellulitis, abscess, wound infection, osteomyelitis, bacteraemia. Never sequence it first. |
| B95.61 | Methicillin susceptible Staphylococcus aureus infection as the cause of diseases classified elsewhere | The MSSA counterpart of B95.62, used the same way when susceptibility testing shows the isolate is not methicillin resistant. |
| A49.02 | Methicillin resistant Staphylococcus aureus infection, unspecified site | Only when the documentation records a MRSA infection but no site and no specific condition. If a site or condition is documented, code that condition plus B95.62 instead. |
| A49.01 | Methicillin susceptible Staphylococcus aureus infection, unspecified site | The MSSA equivalent of A49.02, subject to the same restriction. |
| Z22.322 | Carrier or suspected carrier of methicillin resistant Staphylococcus aureus | Colonisation, not infection — a positive screening swab in someone with no signs of infection. Do not assign it alongside an active MRSA infection code for the same encounter. |
| Z22.321 | Carrier or suspected carrier of methicillin susceptible Staphylococcus aureus | MSSA colonisation, including routine nasal screening results. |
| J15.212 | Pneumonia due to methicillin resistant Staphylococcus aureus | A combination code: it captures both the pneumonia and the organism, so no additional B95.62. J15.211 is the MSSA version. |
| A41.02 | Sepsis due to methicillin resistant Staphylococcus aureus | Another combination code — do not add B95.62. Add codes for any acute organ dysfunction (R65.20 / R65.21) when severe sepsis is documented. A41.01 is the MSSA version. |
| R78.81 | Bacteremia | For a positive blood culture without documented sepsis. Add B95.62 to identify MRSA as the organism. |
| L02.- / L03.- | Cutaneous abscess, furuncle and carbuncle / cellulitis | Site-specific skin codes. Sequence the skin code first, then B95.62 to name the organism. |
| T81.4- | Infection following a procedure | Surgical-site infection, with the appropriate seventh character, plus a code for the specific infection and B95.62 for the organism. |
| Z16.11 | Resistance to penicillins | Not used with MRSA codes. Resistance is already built into B95.62, A49.02 and the combination codes, so adding a Z16 code duplicates it. |
Codes shown are ICD-10-CM, the United States clinical modification. Always verify against the current official code set and guidelines for the encounter's date of service.
The three sequencing rules that cause most errors
- B95.62 never goes first. It is an "as the cause of diseases classified elsewhere" code, so the condition — the abscess, cellulitis, osteomyelitis, wound infection or bacteraemia — is sequenced first.
- Do not pair A49.02 with B95.62. A49.02 is for a MRSA infection with no documented site. Once a site or condition is documented, that condition plus B95.62 replaces it.
- Combination codes stand alone. J15.212 (MRSA pneumonia) and A41.02 (MRSA sepsis) already name the organism, so adding B95.62 duplicates it.
Infection vs colonisation
The distinction decides between an infection code and Z22.322. A positive nasal or skin swab in a patient with no clinical signs is colonisation, coded as carrier status. Documented signs of infection — purulence, spreading erythema, fever, a positive culture from a clinical specimen — move the encounter to an infection code. Where the record shows both a treated infection and separately documented ongoing carriage, follow payer and facility guidance and query the physician rather than assuming.
How the underlying swabs and cultures work is covered on MRSA testing, and the susceptibility result that separates MRSA from MSSA is explained on MSSA vs MRSA.
Worked examples
- MRSA cellulitis of the left lower leg — L03.116 (cellulitis of left lower limb) followed by B95.62.
- MRSA abscess of the right axilla — L02.413 (cutaneous abscess of right axilla) followed by B95.62.
- MRSA ventilator-associated pneumonia — J95.851 (ventilator-associated pneumonia) with J15.212 to identify the pneumonia due to MRSA.
- Severe sepsis due to MRSA with acute kidney injury — A41.02, then R65.20, then N17.9.
- Positive MRSA screening swab, no infection — Z22.322 alone.
- MRSA bacteraemia from an infected central line — T80.211- (bloodstream infection due to central venous catheter), R78.81 and B95.62 as documentation supports.
The clinical picture behind these examples is described on MRSA bacteraemia, MRSA pneumonia and MRSA sepsis.
Documentation that makes coding straightforward
- The specific condition and anatomical site, with laterality.
- Whether MRSA reflects infection or colonisation, stated explicitly.
- The organism as reported by the laboratory, and whether it is methicillin resistant or susceptible.
- For sepsis, a clear statement of sepsis or severe sepsis and each associated organ dysfunction.
- For post-procedural infection, the relationship to the procedure and the device involved.
ICD-10 vs ICD-10-CM vs ICD-11
WHO's ICD-10 carries no MRSA-specific code; the B95.6 category simply identifies Staphylococcus aureus as a cause. The resistance-specific codes above are ICD-10-CM, the version used in the United States. ICD-11, in use in a growing number of countries, handles resistance through separate extension codes rather than the fifth-character split used in ICD-10-CM.
Frequently asked questions
What is the ICD-10 code for MRSA?
What is the difference between B95.62 and A49.02?
What is the ICD-10 code for MRSA colonization?
Can you code Z22.322 and B95.62 together?
What is the ICD-10 code for MRSA pneumonia?
What is the ICD-10 code for MRSA sepsis?
How do you code a MRSA wound or skin infection?
Should Z16.11 be added to show antibiotic resistance?
Is there a single ICD-10 code for MRSA bacteremia?
Symptoms hub
Overview of MRSA symptoms and day-by-day progression.
What does MRSA look like?
Bumps, boils, abscesses and cellulitis — every visual form.
MRSA rash
Does MRSA cause a rash? Look-alikes and how to tell them apart.
MRSA in the nose
Nasal carriage vs infection, swab testing and mupirocin treatment.
MRSA skin infection
Types, diagnosis, treatment, and when skin MRSA becomes dangerous.
MRSA boil
Deep, painful, pus-filled lumps and how they are drained.
MRSA cellulitis
Spreading deeper-skin infection and urgent warning signs.
MRSA folliculitis
Small pus-filled bumps around hair follicles and prevention.
MRSA pneumonia
Hospital, ventilator-associated and necrotising lung infection.
MRSA bacteremia
MRSA in the bloodstream — how it gets there and how it's treated.
MRSA sepsis
Can MRSA cause sepsis? Warning signs and survival rates.
Invasive MRSA
How MRSA reaches the bloodstream, lungs and bone.
MRSA test
PCR nasal swab, wound culture and susceptibility testing.
MSSA vs MRSA
Same bacterium, different antibiotic susceptibility.
Staph infection vs pimple
How to tell a normal pimple from a staph or MRSA skin lesion.
MRSA colonization
Carriers, nasal swabs, how long carriage lasts and when it is treated.
MRSA UTI
MRSA in the urinary tract — catheters, symptoms and treatment.
Scalded skin syndrome
The staph toxin illness that makes a child's skin blister and peel.
Can MRSA kill you?
Death rates by infection type, who is at risk and the warning signs.
Staph infection
Staphylococcus aureus infection overall — symptoms, spread and treatment.
What does a staph infection look like?
Every form on the skin, stage by stage, and the look-alikes.
Is a staph infection contagious?
How it spreads, how long for, and the school, work and sport rules.
Antibiotics for a staph skin infection
Which drugs cover staph and MRSA, course lengths and allergy options.
- CDC / National Center for Health Statistics. ICD-10-CM Official Guidelines for Coding and Reporting (2025)
- CMS. ICD-10-CM code files and tabular list (2025)
- WHO. ICD-10 international classification of diseases, 10th revision (2019)
- CDC. Methicillin-resistant Staphylococcus aureus (MRSA) clinical overview (2024)
